Antimicrobial wild type distributions of microorganisms

Mic distributions include collated data from multiple sources, geographical areas and time periods and can never be used to infer rates of resistance

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Method

MIC distributions for Delafloxacin, 2024-06-21

Antimicrobial: Delafloxacin (Method: MIC)

0.002 0.004 0.008 0.016 0.03 0.06 0.125 0.25 0.5 1 2 4 8 16 32 64 128 256 512 Distributions Observations (T)ECOFF Confidence interval
Acinetobacter baumannii 0 0 0 4 27 84 149 127 60 32 71 133 216 182 146 0 0 157 75 5 1463 1 0.25 - 2
Citrobacter freundii 0 0 0 4 43 104 38 26 39 48 45 15 16 18 0 0 0 0 0 3 396 (0.25) 0.06 - 0.25
Citrobacter koseri 0 0 4 42 277 107 38 21 3 4 1 4 3 1 0 0 0 0 1 4 506 (0.125) 0.03 - 0.125
Enterobacter cloacae 0 4 7 22 160 972 979 193 85 60 88 110 78 54 0 0 0 36 30 8 2878 0.5 0.125 - 0.5
Enterococcus faecalis 0 2 7 15 72 471 813 258 95 202 86 4 0 0 78 0 0 0 0 5 2103 0.5 0.125 - 0.5
Enterococcus faecium 0 0 2 1 9 22 24 18 6 22 39 49 41 250 609 0 0 0 0 3 1092 ID
Escherichia coli 0 29 120 1288 3862 1898 491 598 270 205 890 1603 749 138 0 0 0 157 27 9 12325 0.125 0.06 - 0.5
Haemophilus influenzae 3123 117 42 20 10 5 6 11 0 0 0 0 0 0 5 0 0 0 0 7 3339 ID
Haemophilus parainfluenzae 215 138 115 33 8 2 8 5 5 1 1 0 0 3 6 0 0 0 0 7 540 ID
Klebsiella aerogenes 0 1 0 4 26 189 360 201 54 34 9 22 7 6 0 0 0 1 2 5 916 0.5 0.25 - 1
Klebsiella oxytoca 0 1 0 0 34 358 505 103 32 8 8 4 2 3 0 0 0 1 0 6 1059 0.5 0.125 - 0.5
Klebsiella pneumoniae 0 5 3 25 311 1872 1516 312 228 201 266 388 292 367 1 1 0 288 247 12 6323 0.25 0.125 - 0.5
Proteus mirabilis 0 1 2 39 408 892 176 37 54 114 213 96 25 8 0 15 1 0 0 7 2081 0.25 0.06 - 0.25
Proteus vulgaris 0 0 1 2 16 14 14 5 2 3 3 1 0 0 0 0 0 0 0 1 61 ID
Pseudomonas aeruginosa 0 19 14 35 81 160 456 2200 2301 737 578 386 306 387 1 0 0 311 159 9 8131 2 0.5 - 4
0.002 0.004 0.008 0.016 0.03 0.06 0.125 0.25 0.5 1 2 4 8 16 32 64 128 256 512 Distributions Observations (T)ECOFF Confidence interval
Staphylococcus aureus 2030 6475 5398 664 71 141 1176 2255 1055 739 297 327 73 3 0 0 0 0 0 5 20704 0.016 0.008 - 0.03
Staphylococcus aureus MRSA 117 1028 1185 141 58 257 1018 1908 894 677 277 291 68 2 0 0 0 0 0 5 7921 0.016
Staphylococcus aureus MSSA 1874 6245 4190 530 52 77 230 425 187 98 33 36 5 1 0 0 0 0 0 5 13983 0.016 0.008 - 0.03
Staphylococcus epidermidis 14 129 247 38 2 24 87 165 110 78 66 6 1 3 0 0 0 0 0 3 970 (0.03) 0.008 - 0.03
Staphylococcus haemolyticus 21 84 93 10 3 1 5 58 105 37 7 1 1 4 0 0 0 0 0 5 430 0.016 0.004 - 0.03
Staphylococcus hominis 71 175 101 8 1 5 21 24 14 15 22 3 0 2 0 0 0 0 0 5 462 0.016 0.008 - 0.03
Staphylococcus lugdunensis 6 15 119 283 66 0 1 0 1 2 0 0 0 0 0 0 0 0 0 5 493 0.06 0.016 - 0.06
Streptococcus agalactiae 35 62 377 890 425 37 8 6 9 6 0 0 0 0 0 0 0 0 0 8 1855 0.06 0.03 - 0.06
Streptococcus anginosus 61 130 169 115 27 3 1 0 0 0 0 0 0 0 0 0 0 0 0 8 506 0.03 0.016 - 0.125
Streptococcus constellatus 12 22 15 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 52 -
Streptococcus dysgalactiae 26 127 347 405 60 5 11 2 0 1 1 0 0 0 0 0 0 0 0 7 985 0.06 0.03 - 0.06
Streptococcus mitis 29 20 54 78 41 10 5 0 1 1 0 0 0 0 0 0 0 0 0 2 239 ID
Streptococcus pneumoniae 48 163 1130 3223 1404 174 42 29 5 4 0 0 0 0 1 0 0 0 0 8 6223 0.06 0.016 - 0.06
Streptococcus pyogenes 32 342 1476 1247 377 33 2 2 0 0 0 0 0 0 0 0 0 0 0 8 3511 0.03 0.016 - 0.06