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MIC and Zone diameter distributions

Mic distributions include collated data from multiple sources, geographical areas and time periods and can never be used to infer rates of resistance.

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MIC distributions for Streptococcus pneumoniae, 2026-08-15

Species: Streptococcus pneumoniae (Method: MIC)
0.002 0.004 0.008 0.016 0.03 0.06 0.125 0.25 0.5 1 2 4 8 16 32 64 128 256 512 Distributions Observations (T)ECOFF Confidence interval
Amoxicillin 2 150 1474 2717 2455 245 210 104 156 372 301 45 32 11 0 0 0 0 0 12 8274 0.06 0.016 - 0.06
Ampicillin 0 16 169 391 97 37 18 12 17 10 28 9 4 1 0 0 0 0 0 5 809 0.06 0.008 - 0.25
Azithromycin 0 2 380 218 1881 17696 27701 1821 236 267 672 2669 3053 2610 1654 571 5543 4094 0 7 71068 0.25 0.03 - 0.25
Benzylpenicillin 105 415 3568 6770 2010 511 332 326 347 421 244 116 5 0 0 0 0 0 0 31 15161 0.06 0.016 - 0.06
Cefaclor 0 0 0 2 11 258 770 945 300 145 52 10 23 51 76 27 11 0 0 7 2681 1 0.25 - 4
Cefalexin 0 0 0 0 0 0 0 1 3 29 7 3 3 0 0 0 1 0 0 1 47 ID
Cefalothin 0 0 0 1 2 13 78 27 8 6 9 1 1 0 0 0 0 0 0 2 146 ID
Cefazolin 0 0 0 0 14 147 30 6 5 3 2 2 0 0 0 0 0 0 0 1 209 ID
Cefdinir 0 0 0 2 80 1908 429 106 46 24 18 87 262 23 1 0 0 0 0 1 2986 ID
Cefixime 0 0 0 0 0 6 282 2426 507 299 299 193 201 380 572 187 39 0 0 5 5391 0.5 0.125 - 0.5
Cefoperazone 0 0 0 0 79 96 14 5 6 5 3 1 1 0 0 0 0 0 0 1 210 ID
Cefoperazone-sulbactam 0 0 0 0 76 100 13 6 5 5 3 1 1 0 0 0 0 0 0 1 210 ID
Cefotaxime 157 551 3539 5816 1117 458 337 254 355 231 81 14 2 3 0 0 0 0 0 26 12915 0.06 0.016 - 0.06
Cefpirome 0 0 2 110 22 23 31 10 21 0 1 0 0 0 0 0 0 0 0 2 220 ID
Cefpodoxime 0 0 49 378 3413 530 220 177 101 176 433 313 19 14 2 0 0 0 0 5 5825 0.125 0.03 - 0.25
0.002 0.004 0.008 0.016 0.03 0.06 0.125 0.25 0.5 1 2 4 8 16 32 64 128 256 512 Distributions Observations (T)ECOFF Confidence interval
Ceftaroline 1 2 10 4 7 5 26 14 28 1 1 0 0 0 0 0 0 0 0 1 99 -
Ceftazidime 0 0 2 0 13 45 89 169 82 26 15 22 27 19 5 0 0 0 0 2 514 ID
Ceftibuten 0 0 0 0 0 0 0 0 0 70 99 101 13 11 0 2 0 12 0 2 308 ID
Ceftobiprole 49 64 1023 2229 536 362 285 532 642 148 15 1 0 0 0 0 0 0 0 9 5886 0.06 0.016 - 0.25
Ceftolozane 0 0 0 2 0 12 91 25 8 2 4 17 6 1 1 0 0 0 0 4 169 (0.5) 0.125 - 1
Ceftolozane-tazobactam 0 0 0 0 2 28 97 24 17 10 21 18 6 1 1 0 0 0 0 5 225 0.5 0.06 - 2
Ceftriaxone 0 4 17 883 1510 157 147 79 102 287 45 4 2 1 0 0 0 0 0 4 3238 (0.06) 0.008 - 0.5
Cefuroxime 0 12 1166 3474 10124 5451 1433 1437 1121 850 693 2306 3169 546 8 2 0 0 0 16 31792 0.125 0.03 - 0.125
Chloramphenicol 0 0 0 0 0 1 2 10 66 647 2485 2805 88 260 25 2 0 0 0 8 6391 8 2 - 8
Ciprofloxacin 0 0 0 0 17 24 125 1524 11083 42571 15746 1319 281 99 153 100 10 0 1 49 73054 4 2 - 4
Clarithromycin 0 0 16 349 10637 7221 61 44 81 384 949 434 593 228 406 5079 590 0 0 5 27072 0.125 0.016 - 0.25
Clindamycin 0 0 2 114 2223 19538 7673 887 67 53 301 558 4786 23 412 728 59 23 0 20 37447 0.25 0.125 - 0.5
Daptomycin 0 0 0 0 3 248 5121 2456 280 25 1 0 0 0 0 0 0 0 0 4 8134 (0.5) 0.125 - 0.5
Delafloxacin 48 163 1130 3223 1404 174 42 29 5 4 0 0 0 0 1 0 0 0 0 8 6223 0.06 0.016 - 0.06
Doxycycline 0 0 0 3 12 299 2500 1206 184 54 65 193 196 56 7 3 0 0 0 7 4778 0.5 0.125 - 0.5
0.002 0.004 0.008 0.016 0.03 0.06 0.125 0.25 0.5 1 2 4 8 16 32 64 128 256 512 Distributions Observations (T)ECOFF Confidence interval
Eravacycline 14 75 398 47 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 539 ID
Ertapenem 99 590 1109 712 106 50 41 98 90 23 2 0 0 1 0 0 0 0 0 7 2921 0.03 0.016 - 0.06
Erythromycin 0 1 4 205 2558 19210 6372 867 94 173 706 1065 856 594 720 548 5513 368 0 28 39847 0.25 0.125 - 0.5
Fosfomycin 0 0 0 0 0 0 0 0 0 0 0 14 28 5 3 0 0 0 0 1 50 ID
Fusidic acid 0 0 0 0 0 0 0 0 0 0 1 26 42 75 13 2 0 0 0 4 159 ID
Gatifloxacin 0 0 0 2 19 136 1381 9548 3082 196 46 43 21 6 0 0 0 0 229 13 14704 1 0.25 - 1
Gemifloxacin 0 2 3 58 190 71 12 1 9 4 1 0 0 0 0 0 0 0 0 3 351 (0.125) 0.03 - 0.25
Gentamicin 0 0 0 0 0 0 0 0 0 0 0 2 13 53 472 230 5 1 0 5 776 ID
Imipenem 55 150 57 47 53 12 20 11 4 0 1 1 0 0 0 0 0 0 0 3 411 ID
Lefamulin 0 0 15 129 796 3551 3949 1611 239 38 3 0 0 0 0 0 0 0 0 12 10331 0.5 0.25 - 1
Levofloxacin 0 0 0 0 0 11 83 380 16773 64788 2568 123 199 378 67 24 4 2 231 18 85631 2 1 - 2
Linezolid 0 0 0 0 0 10 35 593 4665 39282 15577 18 0 0 0 0 0 0 0 18 60207 2 1 - 4
Meropenem 18 275 205 50 20 18 17 39 28 4 0 0 1 0 0 0 0 0 0 5 675 0.016 0.004 - 0.03
Minocycline 0 0 0 8 420 2023 1027 169 77 27 21 58 92 119 21 0 0 0 0 9 4062 0.25 0.06 - 0.5
Moxifloxacin 0 0 1 12 167 3570 18152 4191 314 36 97 67 17 1 0 0 0 0 233 26 27471 0.5 0.125 - 0.5
0.002 0.004 0.008 0.016 0.03 0.06 0.125 0.25 0.5 1 2 4 8 16 32 64 128 256 512 Distributions Observations (T)ECOFF Confidence interval
Netilmicin 0 0 0 0 0 0 0 0 0 0 0 4 8 7 3 2 1 0 0 1 25 ID
Norfloxacin 0 0 0 0 0 0 0 0 0 9 57 287 299 47 2 0 0 0 0 1 701 ID
Ofloxacin 0 0 0 0 0 0 0 10 75 914 3293 194 2 18 6 0 0 0 0 7 4512 4 2 - 4
Omadacycline 0 0 0 8 7357 13374 2977 458 74 3 0 0 0 0 0 0 0 0 0 10 24251 0.25 0.125 - 0.25
Oxacillin 0 0 0 0 19 81 216 74 31 3 3 4 8 7 1 0 0 0 0 2 447 ID