Antimicrobial wild type distributions of microorganisms

Mic distributions include collated data from multiple sources, geographical areas and time periods and can never be used to infer rates of resistance

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Method

MIC distributions for Escherichia coli, 2024-04-30

Species: Escherichia coli (Method: MIC)

0.002 0.004 0.008 0.016 0.03 0.06 0.125 0.25 0.5 1 2 4 8 16 32 64 128 256 512 Distributions Observations (T)ECOFF Confidence interval
Flumequine 0 0 0 0 0 0 1 37 1651 446 31 88 288 192 28 37 40 0 0 10 2839 2 0.5 - 2
Fosfomycin 0 0 0 0 0 0 73 349 588 791 253 77 68 45 38 18 25 24 2 11 2351 4 1 - 4
Gatifloxacin 1 35 206 1034 677 177 53 75 38 13 28 139 123 46 17 2 2 0 0 4 2666 (0.125) 0.03 - 0.125
Gentamicin 0 0 4 6 25 49 522 8516 32023 20499 3360 799 1362 3725 6360 512 138 166 70 82 78136 2 1 - 2
Imipenem 0 0 36 91 315 4895 14910 9106 2047 433 212 68 21 22 8 10 2 0 0 57 32176 0.5 0.25 - 0.5
Imipenem-relebactam 0 0 0 0 0 1424 10067 988 256 80 9 10 13 5 7 0 0 0 0 2 12859 ID
Kanamycin 0 0 0 0 0 0 3 127 333 368 720 1238 507 107 59 181 34 183 0 4 3860 (16) 4 - 32
Levofloxacin 0 0 4 81 1091 752 176 70 111 32 10 33 100 208 108 2 0 0 0 5 2778 0.125 0.03 - 0.25
Loracarbef 0 0 0 0 0 0 0 10 122 288 90 22 7 4 4 2 0 0 1 2 550 ID
Mecillinam 0 0 0 0 7 225 667 241 125 115 51 18 17 5 5 7 6 8 5 4 1502 (0.5) 0.25 - 0.5
Meropenem 0 0 670 3929 2296 273 78 45 16 15 11 11 13 14 16 9 0 0 0 45 7396 0.06 0.03 - 0.06
Meropenem-vaborbactam 0 0 1 46 7 4 1 5 4 8 4 4 9 8 6 7 0 0 0 2 114 ID
Minocycline 0 0 0 0 0 0 1 16 212 588 292 113 82 138 48 8 0 0 0 6 1498 4 2 - 8
Moxifloxacin 0 0 9 78 472 809 132 62 92 46 17 19 79 188 180 2 0 1 0 5 2186 0.25 0.06 - 0.5
Nalidixic acid 0 0 0 0 0 0 0 0 192 4751 23654 8395 441 124 151 1227 288 94 0 10 39317 8 4 - 8
0.002 0.004 0.008 0.016 0.03 0.06 0.125 0.25 0.5 1 2 4 8 16 32 64 128 256 512 Distributions Observations (T)ECOFF Confidence interval
Neomycin 0 0 0 0 0 0 0 1 4 1475 1421 741 94 17 91 61 21 20 0 15 3946 8 1 - 8
Netilmicin 0 0 0 0 0 0 9 1405 2583 1286 344 95 108 76 44 20 2 3 0 4 5975 (2) 1.000 - 4.000
Nitrofurantoin 0 0 0 0 0 0 0 0 0 1 15 155 1304 2068 338 97 17 5 0 10 4000 64 16 - 64
Norfloxacin 0 0 0 24 116 433 51 3 24 1 0 0 0 0 1 1 0 0 0 2 654 ID
Ofloxacin 0 0 0 8 275 1878 629 82 110 135 33 12 131 94 290 3 0 0 0 5 3680 0.25 0.06 - 0.25
Omadacycline 0 0 0 0 0 0 30 1069 8221 6520 3028 1044 15 17 2 201 0 0 0 6 20147 4 1 - 8
Piperacillin 0 0 0 0 0 6 16 38 312 4820 6883 1214 382 776 1335 1137 1184 2043 1288 14 21434 8 2 - 8
Piperacillin-tazobactam 0 0 8 6 8 45 99 212 2970 16358 20882 5478 1855 1224 799 533 757 236 89 65 51559 8 4 - 16
Sitafloxacin 2 10 57 26 25 23 12 15 6 26 22 12 2 2 0 0 0 0 0 5 240 0.03 0.004 - 0.06
Spectinomycin 0 0 0 0 0 0 0 0 0 0 0 7 132 2070 342 200 357 581 0 14 3689 64 16 - 64
Streptomycin 0 0 0 0 0 0 0 0 0 76 586 2269 3099 1028 446 1085 1124 166 38 26 9917 16
Sulbactam 0 0 0 0 0 0 0 0 3 1 0 0 8 51 395 109 35 11 16 1 629 -
Sulfamethoxazole 0 0 0 0 0 0 0 0 0 0 24 62 250 477 254 42 6 2 318 1 1435 ID
Temocillin 0 0 0 0 0 0 2 1 18 136 490 1261 1057 395 113 52 29 79 31 31 3664 16 16 - 32
Tetracycline 0 0 0 0 0 0 2 20 321 3377 8098 1670 190 656 1258 1078 1336 905 6 64 18917 8 2 - 4
0.002 0.004 0.008 0.016 0.03 0.06 0.125 0.25 0.5 1 2 4 8 16 32 64 128 256 512 Distributions Observations (T)ECOFF Confidence interval
Ticarcillin-clavulanic acid 0 0 0 0 0 0 0 0 1 8 46 37 12 22 22 41 66 134 0 1 389 ID
Tigecycline 0 0 190 170 725 17910 46730 30613 9797 2725 825 40 6 13 2 1 0 0 0 33 109747 0.5 0.25 - 1
Tobramycin 0 0 0 2 7 14 103 1107 9173 12724 4422 922 472 363 262 141 14 9 70 37 29805 4 1 - 4
Trimethoprim 0 0 0 0 0 85 292 1012 1956 866 146 53 21 214 471 0 2 6 205 14 5329 2 1 - 4
Trimethoprim-sulfamethoxazole 0 0 4 44 521 2374 1620 694 416 134 45 15 5 3 1343 602 19 0 0 11 7839 0.5 0.125 - 1