Antimicrobial wild type distributions of microorganisms

Mic distributions include collated data from multiple sources, geographical areas and time periods and can never be used to infer rates of resistance

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Method

MIC distributions for Escherichia coli, 2024-10-12

Species: Escherichia coli (Method: MIC)

0.002 0.004 0.008 0.016 0.03 0.06 0.125 0.25 0.5 1 2 4 8 16 32 64 128 256 512 Distributions Observations (T)ECOFF Confidence interval
Amikacin 0 0 0 2 1 0 1 28 329 4723 15660 6316 1134 191 56 36 4 5 45 21 28531 8 4 - 8
Amoxicillin 0 0 0 0 0 0 0 0 9 94 735 1614 511 24 6 718 611 53 275 19 4650 8 8 - 16
Amoxicillin-clavulanic acid (fixed) 0 0 0 0 0 0 0 0 0 419 2121 3316 1786 997 501 313 230 389 65 3 10137 (8) 2 - 64
Ampicillin 0 0 0 0 0 0 6 21 152 5308 30179 28801 4002 749 16843 11012 1527 6687 196 53 105483 8 4 - 16
Ampicillin-sulbactam (fixed) 0 0 0 0 0 0 0 0 2 20 12 1 0 2 3 3 7 0 0 1 50 ID
Ampicillin-sulbactam (ratio) 0 0 0 0 0 0 6 11 71 393 2935 1949 744 1998 1605 1085 0 0 0 2 10797 ID
Azithromycin 0 0 0 0 0 0 0 3 36 269 2762 6548 907 31 28 0 0 0 0 3 10584 (16) 4 - 16
Aztreonam 0 0 0 4 486 846 581 121 32 14 18 29 25 18 18 58 0 0 0 3 2250 (0.25) 0.016 - 1
Aztreonam-avibactam 0 0 0 6153 12260 8951 1719 348 150 167 201 195 83 36 10 8 6 0 0 5 30287 0.125 0.06 - 0.25
Cefaclor 0 0 0 0 0 0 0 2 31 60 25 22 3 0 4 2 0 1 0 1 150 ID
Cefadroxil 0 0 0 0 0 0 0 0 0 0 0 8 60 54 18 1 3 2 0 2 146 ID
Cefalexin 0 0 0 0 0 0 0 0 1 0 7 89 124 25 17 1 3 0 0 3 267 (32) 4 - 32
Cefaloridine 0 0 0 0 0 0 0 0 1 5 17 30 28 1 14 0 0 0 0 1 96 ID
Cefalothin 0 0 0 0 0 0 0 0 4 47 227 1005 2578 1644 468 389 53 10 8 15 6433 32 16 - 64
Cefazolin 0 0 0 0 0 0 0 0 37 142 113 41 18 11 17 1 1 0 0 5 381 4 0.5 - 16
0.002 0.004 0.008 0.016 0.03 0.06 0.125 0.25 0.5 1 2 4 8 16 32 64 128 256 512 Distributions Observations (T)ECOFF Confidence interval
Cefepime 0 0 99 509 4181 4342 1263 406 203 139 141 223 264 233 255 251 292 159 497 35 13457 0.125 0.06 - 0.25
Cefepime-enmetazobactam-8 0 0 13 350 2631 1540 376 118 30 10 5 6 4 2 1 0 2 0 0 8 5088 0.125 0.06 - 0.125
Cefepime-tazobactam 3 0 24 784 4732 2462 627 203 91 75 54 30 17 11 6 24 88 2 2 3 9235 (0.25) 0.03 - 0.5
Cefepime-zidebactam 1 48 20 557 6226 2231 1534 242 30 10 7 1 0 0 0 0 0 0 0 3 10907 (0.125) 0.03 - 0.125
Cefixime 0 0 3 4 22 101 152 116 77 30 11 11 7 4 4 3 1 1 1 4 548 (1) 0.25 - 8
Cefoperazone 0 0 0 0 0 22 122 165 50 59 26 17 12 26 6 13 20 159 0 3 697 (1) 0.25 - 2
Cefoselis 0 0 1 23 144 113 50 11 4 2 3 3 4 7 6 10 13 38 69 5 501 0.125 0.06 - 0.5
Cefotaxime 0 5 37 303 1618 4952 2362 470 189 80 49 47 38 52 71 131 24 31 28 44 10487 0.25 0.125 - 0.25
Cefotaxime-clavulanate 0 0 15 13 125 165 90 16 6 5 6 2 1 1 10 0 0 1 0 8 456 0.25 0.125 - 1
Cefoxitin 0 0 0 0 0 0 2 29 182 4486 28143 40880 12412 2912 1998 1873 15 12 0 26 92944 16 8 - 32
Cefpirome 0 0 1 234 1503 2359 1023 268 88 47 46 20 9 14 16 9 86 5 0 7 5728 0.25 0.06 - 0.25
Cefpodoxime 0 0 0 0 0 0 66 571 722 161 51 21 15 12 19 13 114 0 0 3 1765 (2) 0.25 - 4
Cefquinome 0 0 0 0 0 275 28 2 2 1 0 0 0 0 0 0 0 0 0 2 308 ID
Cefradine 0 0 0 0 0 0 0 0 0 0 0 0 44 31 21 0 0 0 0 1 96 ID
Ceftaroline 0 0 0 0 102 256 153 67 37 21 10 5 9 3 59 0 0 0 0 2 722 ID
0.002 0.004 0.008 0.016 0.03 0.06 0.125 0.25 0.5 1 2 4 8 16 32 64 128 256 512 Distributions Observations (T)ECOFF Confidence interval
Ceftazidime 0 0 14 42 182 1627 5417 5277 1202 311 180 138 123 144 142 81 132 19 5 71 15036 1 0.25 - 1
Ceftazidime-avibactam 0 0 1 1 4 27 61 36 27 30 33 17 8 4 1 2 28 13 0 3 293 ID
Ceftazidime-clavulanate 0 0 23 30 120 484 856 652 160 39 32 26 35 15 8 16 2 1 0 39 2499 1 0.25 - 1
Ceftibuten 0 0 2 25 62 532 1361 1993 583 139 80 54 95 94 35 56 0 1 0 5 5112 1 0.5 - 2
Ceftiofur 0 0 0 0 0 0 1681 16241 15649 869 166 436 1190 626 0 0 0 0 0 12 36858 1 0.5 - 1
Ceftobiprole 0 0 3 326 3050 1634 298 86 28 22 4 10 17 369 23 136 29 0 0 8 6035 0.125 0.06 - 0.125
Ceftolozane 0 0 0 0 1 8 730 1018 807 54 40 121 148 139 215 463 0 0 0 5 3744 1 0.25 - 8
Ceftolozane-tazobactam 0 0 0 0 1 80 1995 1820 682 336 116 69 45 27 27 17 0 0 0 11 5215 1 0.5 - 4
Ceftriaxone 0 0 28 144 461 220 33 8 3 2 2 2 2 0 3 0 0 0 0 4 908 (0.125) 0.03 - 0.5
Cefuroxime 0 0 1 1 1 5 93 161 1475 4624 20855 46657 14450 3200 3773 263 260 98 73 29 95990 8 8 - 16
Chloramphenicol 0 0 0 0 0 0 0 0 0 2 2336 21965 19115 752 305 736 387 254 0 40 45852 16 8 - 16
Ciprofloxacin 14 189 3952 7238 1355 356 401 521 171 94 47 119 246 229 564 166 85 59 7 53 15667 0.06 0.03 - 0.06
Colistin 0 0 0 0 0 2 231 2058 2747 845 56 16 14 5 8 2 30 0 0 13 6014 2 0.25 - 2
Delafloxacin 0 29 120 1288 3862 1898 491 598 270 205 890 1603 749 138 0 0 0 157 27 9 12325 0.125 0.06 - 0.5
Doripenem 0 0 6 407 1850 95 13 4 0 0 0 1 0 0 0 0 0 0 0 4 2376 (0.06) 0.016 - 0.06
0.002 0.004 0.008 0.016 0.03 0.06 0.125 0.25 0.5 1 2 4 8 16 32 64 128 256 512 Distributions Observations (T)ECOFF Confidence interval
Doxycycline 0 0 0 0 0 0 14 38 393 1923 1650 432 1008 1732 555 142 6 1 0 17 7894 4 4 - 8
Enrofloxacin 0 0 0 0 832 1994 153 20 26 11 1 1 1 0 0 0 0 0 0 11 3039 0.125
Eravacycline 0 0 0 21 2 162 938 469 96 20 5 1 0 0 0 0 0 0 0 6 1714 0.5 0.25 - 1
Ertapenem 0 40 691 178 42 23 10 2 0 0 0 0 2 0 0 0 0 0 0 4 988 (0.03) 0.008 - 0.03
Florfenicol 0 0 0 0 0 0 1 1 2 16 559 7207 7176 633 51 67 212 162 105 106 16192 16 8 - 16